TLB Standalone Cannot be Terminated by Windows 7

Sometimes TLB standalone on Windows 7 hangs. I am offered a box and choose to close the program. But I then cannot restart the program, because the result is a message stating that TLB is already running. Even in process explorer, attempting to terminate the TLBhost.exe process does not work. The process will not terminate. That leaves me no choice but to log off and on or reboot.